RecruitingPhase 2NCT06477419

A Study of Sacituzumab Govitecan in People With Mesothelioma

Phase 2 Study of Sacituzumab Govitecan-hziy in Patients With Previously Treated Mesothelioma


Sponsor

Memorial Sloan Kettering Cancer Center

Enrollment

33 participants

Start Date

Jun 21, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Participants will receive sacituzumab govitecan until their disease gets worse (progresses), they have severe side effects and cannot continue study treatment, or the participants or the study doctor thinks it's in your best interest to stop treatment.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests sacituzumab govitecan — an antibody-drug therapy that targets cancer cells and delivers chemotherapy directly to them — in patients with pleural mesothelioma, a rare cancer of the lung lining often linked to asbestos exposure. **You may be eligible if...** - You are 18 or older - You have been confirmed to have diffuse pleural mesothelioma - You have already received at least one prior treatment (including a platinum-based therapy) - Your overall health is adequate to tolerate treatment **You may NOT be eligible if...** - You have never received prior systemic treatment - Your organ function is too impaired to handle the drug safely - You have certain other serious medical conditions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSacituzumab govitecan-hziy

After enrollment, participants will receive SG until disease progression or intolerable toxicity.


Locations(7)

Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, United States

Memorial Sloan Kettering Monmouth

Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen

Montvale, New Jersey, United States

Memorial Sloan Kettering Cancer Center @ Commack

Commack, New York, United States

Memorial Sloan Kettering Westchester

Harrison, New York, United States

Memorial Sloan - Kettering Cancer Center

New York, New York, United States

Memorial Sloan Kettering Nassau

Uniondale, New York, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT06477419


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