RecruitingNCT06478303

LAnguage-Motor Imagery Circuits to Improve Motor Learning and Language Comprehension


Sponsor

University Hospital, Grenoble

Enrollment

105 participants

Start Date

Jul 27, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Recent evidence suggests that cognitive systems do not operate in isolation but interact within broader networks, thus opening new avenues for fundamental and clinical research. An illustrative example is the interaction between language comprehension and motor representations. For instance, motor training (e.g., sports, origami training) can facilitate action verb recognition, whereas motor deficits (e.g., upper limb immobilization) can hinder the processing of action language. Similarly, action language has been shown to affect motor performance. These effects are attributed to an implicit form of motor imagery, an automatic simulation of motor experience (without actual movement) evoked by action words. Interestingly, literature supports the idea that the motor simulations used for imagining an action are also engaged during the reading of action language, leading to similar neurophysiological and behavioral changes in both processes. However, questions remain about the similarity of the simulations generated by motor imagery and action language. This project, encompassing three experimental sequences, aims to address these questions to achieve significant scientific advancements in both theoretical and applied domains.


Eligibility

Min Age: 18 YearsMax Age: 40 Years

Inclusion Criteria7

  • persons who have given written consent,
  • healthy subjects
  • subjects reading and understanding French
  • right-handed,
  • affiliated with a social security system,
  • between 18 and 40 years old,
  • had completed the TMS inclusion questionnaire or had undergone a medical examination prior to participation in the MRI study.

Exclusion Criteria6

  • Existence of a severe general medical condition: cardiac, respiratory, hematological, renal, hepatic, cancerous,
  • Regular use of anxiolytics, sedatives, antidepressants, neuroleptics,
  • Characterized psychiatric pathology,
  • Ingestion of alcohol prior to the examination,
  • Persons covered by articles L1121-5 to L1121-8 of the CSP,
  • Presence of contraindications to MRI or TMS.

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Interventions

OTHERMotor imagery

Participants were asked to imagine arm or foot movements.

OTHERAction reading

Participants were asked to read sentences involving arm or foot movements

OTHERMotor localizer

Participants were asked to perform arm or foot movements


Locations(2)

CHU Grenoble Alpes

Grenoble, Grenob, France

Université de Bourgogne

Dijon, France

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NCT06478303


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