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RecruitingPhase 4NCT06479720

Efficacy of Solifenacin or Mirabegron With Local Estrogen Versus Combination Pharmacotherapy for Overactive Bladder

Efficacy and Safety of Solifenacin or Mirabegron With Local Estrogen Versus Combination Treatment With Mirabegron and Solifenacin for Refractory Overactive Bladder

Sponsor

Mackay Memorial Hospital

Enrollment

300 participants

Start Date

Jun 16, 2022

Study Type

INTERVENTIONAL

Conditions

Effect of DrugUrinary Bladder, Overactive

Summary

To investigates the effects of solifenacin or mirabegron with local estrogen versus combination treatment with solifenacin and mirabegron in women with overactive bladder

Eligibility

Sex: FEMALEMin Age: 40 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Combined pharmacotherapy with Solifenacin and Mirabegron, a drug called Mirabegron with vaginal estrogen cream, and others for people with effect of drug and urinary bladder, overactive. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 40 Years to 90 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCombined pharmacotherapy with Solifenacin and Mirabegron

Solifenacin (5mg) is anticholinergic and Mirabegron (25mg) is a beta-3 adrenergic agonist.

DRUGSolifenacin with vaginal estrogen cream

Solifenacin (5mg) is anticholinergic. Premarin, vaginal conjugated equine estrogen vaginal cream (0.625 mg).

DRUGMirabegron with vaginal estrogen cream

Mirabegron (25mg) is a beta-3 adrenergic agonist. Premarin, vaginal conjugated equine estrogen vaginal cream (0.625 mg).

Locations(1)

Mackay Memorial Hospital

Taipei, Taiwan

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NCT06479720

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