RecruitingNot ApplicableNCT06487247

HEME Home Transfusion Program

Supportive Transfusion Program for Patients With Hematologic Malignancies: A Cluster Randomized Trial


Sponsor

Dana-Farber Cancer Institute

Enrollment

700 participants

Start Date

Sep 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This research study is evaluating whether a new care delivery program that provides access to home blood transfusions in hospice (i.e, HEME-Hospice) compared to regular standard of care improves quality of life, mood, and end-of-life health care utilization for patients with hematologic malignancies.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This program is studying whether delivering blood transfusions at home — rather than in a clinic or hospital — is feasible, safe, and preferred by people with advanced blood cancers who need regular transfusions near the end of life. **You may be eligible if...** - You are 18 or older - You have a relapsed or treatment-resistant blood cancer - You receive your primary blood cancer care at Dana-Farber Cancer Institute - You have already had at least one red blood cell or platelet transfusion without a serious reaction - Your doctor estimates you have six months or less to live - You live within the service area of Care Dimensions Hospice - Family caregivers of eligible patients may also participate **You may NOT be eligible if...** - You are already enrolled in hospice - You live in a nursing home or assisted living facility - You have had a previous serious adverse reaction to a blood transfusion - You are under 18 years old Talk to your doctor to see if this trial is right for you.

This is a simplified summary. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALHEME-Hospice Program

A care delivery program that combines home-based transfusions with routine home hospice care. Transfusions are administered by trained transfusion nurses. Standard hospice care is provided by an interdisciplinary team of non-transfusion nurse case managers, hospice aides, social workers, and chaplains.


Locations(2)

Brigham and Women's Hospital

Boston, Massachusetts, United States

Dana-Farber Cancer Institute

Boston, Massachusetts, United States

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NCT06487247


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