SIM0718 Treatment of Asthma Clinical Study

This study is testing a new injectable biologic drug called SIM0718 in people with moderate to severe asthma that is not well controlled despite taking inhaled corticosteroids and other controller medications. Researchers want to see if this drug safely reduces asthma attacks and improves lung function. **You may be eligible if...** - You are 12 to 75 years old (weighing at least 40 kg) with an asthma diagnosis for at least 12 months - You are currently on medium or high-dose inhaled steroids plus one or two additional controller medications - Your lung function is reduced (as measured by breathing tests) - Your asthma is not well controlled and you have had at least one severe flare-up in the past year **You may NOT be eligible if...** - You are a current smoker or have a significant smoking history - You have another serious lung condition (like COPD) - You have significant heart, liver, or immune system problems - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.