RecruitingNCT06489665

Imaging Quality and Potential Clinical Relevance of Phase Contrast Mammography In-vivo: a Single-center, Prospective Study

Imaging Quality and Potential Clinical Relevance of Phase Contrast

Sponsor

University of Zurich

Enrollment

350 participants

Start Date

Oct 17, 2024

Study Type

OBSERVATIONAL

Conditions

Breast Cancer Microcalcification Image

Summary

Conventional mammography, breast sonography and breast MRI have specific weaknesses. In particular, mammography has a low sensitivity for the detection of mammary carcinoma in patients with a dense breast. Phase contrast mammography could help to overcome some of these limitations. Observational study.

Eligibility

Min Age: 18 Years

Inclusion Criteria10

\>18 years
Mastectomy, tumorectomy or biopsy planned
Informed consent of the patient
\>18 years
BI-RADS 5 (highly suggestive of malignancy at ultrasound or mammography) or 6 (known biopsy proven malignancy);
Scheduled for mastectomy or breast conserving surgery with radiotherapy.
Informed consent of the patient
\>40 years
undergoing mammography for screening or diagnostic purpose.
Informed consent of the patient

Exclusion Criteria5

Breast implants. The women will be asked, if they have a breast-implant.
Inability to understand the study procedure due to cognitive or linguistic deficits.
Pregnancy
Breast-feeding.
Re-staging after neoadjuvant chemotherapy. Patients who participated in prior research projects with ionizing radiation in the past 12 months