RecruitingPhase 4NCT06492512
Oral Iron Supplementation on Alternate vs. Consecutive Days for Iron Deficiency Anemia in Pregnancy
Sponsor
Southern Illinois University
Enrollment
120 participants
Start Date
May 27, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
This will be a randomized clinical trial. Enrolled subjects will be randomized (1:1) into two study arms to receive either daily (Group 1) or alternate day (Group 2) supplementation with one oral pill containing ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill.
Eligibility
Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years
Inclusion Criteria1
- Pregnant patients will be enrolled at less than 30 weeks gestational age (GA) with laboratory confirmed IDA (as defined by hemoglobin under 10.5 g/dL, as well as ferritin under 15 mcg/L)
Exclusion Criteria1
- Patients <18 years old, patients who have severe IDA that requires blood transfusion or IV iron infusion, patients who have other known hemoglobinopathy (such as thalassemia or sickle cell anemia) or anemia of different mechanism (such as vitamin B12 or folate deficiency), patients with ulcerative colitis, Crohn's disease, gastric ulcers, patients who have previously undergone gastric bypass surgery, patients who experience admission for antepartum bleed, have been diagnosed with abnormal placentation (i.e., placenta previa, placenta accreta, placenta increta or percreta)
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Interventions
DRUGdaily ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill
ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill daily
DRUGalternate day ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill
ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill every other day
Locations(1)
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NCT06492512
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