RecruitingNot ApplicableNCT06492785

Hyaluronic Acid-enriched Transfer Medium in Single Blastocyst Transfer

Use of Hyaluronic Acid-enriched Transfer Medium in Women Undergoing Single Blastocyst Transfer : a Multicenter, Randomized Controlled Trial


Sponsor

Northwest Women's and Children's Hospital, Xi'an, Shaanxi

Enrollment

858 participants

Start Date

Sep 13, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to compare the live birth rates of high concentration of Hyaluronic Acid (0.5 mg/ml) transfer medium (EmbryoGlue®) to those containing low Hyaluronic Acid concentrations (0.125 mg/ml) (G2 medium) in women undergoing single fresh and frozen blastocyst transfer.


Eligibility

Inclusion Criteria4

  • All cycles with single blastocyst transfer will be considered eligible
  • Both fresh and cryopreserved embryo transfer cycles utilizing autologous oocytes
  • No age restriction will be applied
  • Informed consent was signed

Exclusion Criteria3

  • Uterine anatomic anomalies
  • Women with untreated hydrosalpines
  • Once couples have been enrolled in the trial, subsequent cycles will not be incorporated.

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Interventions

BIOLOGICALHigh Hyaluronic Acid concentrations (0.5 mg/ml)

Hyaluronic Acid(EmbryoGlue®)

BIOLOGICALLow Hyaluronic Acid concentrations (0.125 mg/ml)

Hyaluronic Acid (G2 medium)


Locations(1)

IVF laboratory

Xi'an, Shaanxi, China

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NCT06492785


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