AI-TOP Study Artificial Intelligence for Trigger Optimization.
An Artificial Intelligence Based Approach for Selecting the Optimal Day for Triggering.
Fundacion Dexeus
644 participants
Apr 8, 2026
INTERVENTIONAL
Conditions
Summary
To evaluate, in a randomized controlled trial, whether AI-guided monitoring and ovulation triggering leads to clinical outcomes comparable to those achieved through physician-led decision-making in patients undergoing ovarian stimulation for IVF.
Eligibility
Inclusion Criteria1
- Undergoing COS for IVF with autologous oocytes, oocyte donation and elective fertility preservation with all monitoring USS (ultrasound scan) conducted at our centers.
Exclusion Criteria2
- Medically indicated fertility preservation
- Inability to attend clinic visits for monitoring.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
The AI algorithm used in this study is STIMAI®. STIMAI® is an artificial intelligence-based software that assists clinicians by providing data-driven insights to optimize the fertility treatment process and support conception. The software is designed as a clinical decision support tool and does not replace the physician's judgment; final clinical decisions will remain under the responsibility of the treating physician The physician will consult the AI application, which predicts the number of MII oocytes for different trigger days. If the algorithm recommends triggering today or tomorrow, the physician will choose which option to follow.
As soon as 2-3 follicles of 17 mm are detected, the physician will determine the timing of ovulation triggering based on clinical judgment.
Locations(5)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07515118