RecruitingNot ApplicableNCT06493968
Role of Uterotonics in Reducing Intraoperative Blood Loss in Patients With PASD Undergoing Cesarean Hysterectomy
Role of Uterotonics in Reducing Intraoperative Blood Loss in Patients With Placenta Accrete Spectrum Disorders Undergoing Cesarean Hysterectomy
Sponsor
Cairo University
Enrollment
70 participants
Start Date
Jul 1, 2024
Study Type
INTERVENTIONAL
Conditions
Summary
Objectives: To evaluate the effect of oxytocin in reducing intraoperative blood loss in patients with PAS disorders planned for cesarean hysterectomy.
Eligibility
Sex: FEMALEMin Age: 20 YearsMax Age: 40 Years
Inclusion Criteria6
- Pregnancy of singleton living fetus
- Previous one or more cesarean sections
- Gestational age: > 32 weeks
- The following ultrasound markers such as "loss of clear retroplacental translucency", "myometrial thinning", "abnormal lacunae", "irregular bladder wall", "utero-vesicalhypervascularity".
- Preoperative hemoglobin more than 10 gm/dl
- Cases with PAS that will undergoing CS Hysterectomy
Exclusion Criteria5
- Maternal medical disorders e.g.: coagulation defects, cardiac diseases etc.….
- Any known or reported hypersensitivity to the used medication.
- All cases with spontaneous placental separation at laparotomy.
- All patients undergoing conservative management of PAS.
- All cases which necessitate emergency termination.
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Interventions
DRUGoxytocin
Uterotonics will be given in the form of an IV bolus of 10 units of oxytocin immediately with the uterine incision
OTHERplacebo
IV bolus of normal saline immediately with the uterine incision
Locations(1)
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NCT06493968
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