RecruitingNot ApplicableNCT06512181

Uterine Preservation in the Management of Placenta Accreta Spectrum Disorders


Sponsor

University of Pennsylvania

Enrollment

15 participants

Start Date

Apr 21, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study for the conservative management of placenta accreta spectrum disorders (PAS), which are a major cause of maternal morbidity and mortality. The most common management strategy for PAS in the United States is a preterm cesarean-hysterectomy. However, accumulating data show that conservative management is safer and is preferred by some patients. In selected participants (n=15) who desire uterine preservation, the investigators provide the option of conservative management, which will be defined as leaving the placenta in the uterus after delivery of the infant. This is a single-arm single-site pilot study where all participants will be carefully monitored during a standard postpartum inpatient stay and with outpatient follow-up until the uterus is empty.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Conservative/Expectant Management for people with placenta accreta spectrum. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERConservative/Expectant Management

At time of caesarean section, participants will not have a hysterectomy, but will be treated clinically to preserve their uterus.


Locations(1)

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

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NCT06512181


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