Uterine Preservation in the Management of Placenta Accreta Spectrum Disorders
University of Pennsylvania
15 participants
Apr 21, 2025
INTERVENTIONAL
Conditions
Summary
This study for the conservative management of placenta accreta spectrum disorders (PAS), which are a major cause of maternal morbidity and mortality. The most common management strategy for PAS in the United States is a preterm cesarean-hysterectomy. However, accumulating data show that conservative management is safer and is preferred by some patients. In selected participants (n=15) who desire uterine preservation, the investigators provide the option of conservative management, which will be defined as leaving the placenta in the uterus after delivery of the infant. This is a single-arm single-site pilot study where all participants will be carefully monitored during a standard postpartum inpatient stay and with outpatient follow-up until the uterus is empty.
Eligibility
Plain Language Summary
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Interventions
At time of caesarean section, participants will not have a hysterectomy, but will be treated clinically to preserve their uterus.
Locations(1)
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NCT06512181