RecruitingPhase 4NCT06495892

PVP-Guided Decongestive Therapy in HF 2

Peripheral Venous Pressure-Guided Decongestive Therapy in Heart Failure 2


Sponsor

Başakşehir Çam & Sakura City Hospital

Enrollment

650 participants

Start Date

Jul 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The investigators hypothesize that a simple assessment of peripheral venous pressure (PVP) will better predict the diuretic need and long-term outcomes (all cause mortality, all cause rehospitalization, emergency department visits) compared to standard evaluation.


Eligibility

Min Age: 18 YearsMax Age: 99 Years

Inclusion Criteria3

  • Hospitalization for heart failure (de novo or decompensated chronic heart failure) irrespective of left ventricular ejection fraction
  • Age 18-99
  • Accept to participate

Exclusion Criteria10

  • A prior history of upper extremity venous disease
  • Serum creatinine ≥ 3.5 mg/dL
  • Severe stenotic valvular disease
  • Hypertrophic obstructive cardiomyopathy
  • Withdrawal of consent
  • Indwelling central venous catheter,
  • Implanted left ventricular assist device
  • History of heart transplantation
  • Clinical diagnosis of cardiogenic shock
  • Any right-to-left shunt

Interventions

DRUGDiuretic therapy

Diuretic therapy will be tailored according to peripheral venous pressure targets or standard approach


Locations(16)

Ankara Etlik City Hospital

Ankara, Turkey (Türkiye)

Antalya Atatürk State Hospital

Antalya, Turkey (Türkiye)

Akdeniz University

Antalya, Turkey (Türkiye)

Trakya University

Edirne, Turkey (Türkiye)

Erzurum Atatürk University Hospital

Erzurum, Turkey (Türkiye)

Eskişehir City Hospital

Eskişehir, Turkey (Türkiye)

Mehmet Akif Ersoy Training and Research Hospital

Istanbul, Turkey (Türkiye)

Basaksehir Cam and Sakura City Hospital

Istanbul, Turkey (Türkiye)

Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital

Istanbul, Turkey (Türkiye)

Bağcılar Training and Research Hospital

Istanbul, Turkey (Türkiye)

Bakırçay University, Faculty of Medicine

Izmir, Turkey (Türkiye)

Pazarcık State Hospital

Kahramanmaraş, Turkey (Türkiye)

Kafkas University Health Research and Application Hospital

Kars, Turkey (Türkiye)

Kütahya Health Sciences University

Kütahya, Turkey (Türkiye)

İdil State Hospital

Şırnak, Turkey (Türkiye)

Tokat Gaziosmanpaşa University

Tokat Province, Turkey (Türkiye)

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NCT06495892


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