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RecruitingPhase 4NCT06495892

PVP-Guided Decongestive Therapy in HF 2

Peripheral Venous Pressure-Guided Decongestive Therapy in Heart Failure 2

Sponsor

Başakşehir Çam & Sakura City Hospital

Enrollment

650 participants

Start Date

Jul 1, 2024

Study Type

INTERVENTIONAL

Conditions

Heart FailureCongestive Heart FailureCongestion

Summary

The investigators hypothesize that a simple assessment of peripheral venous pressure (PVP) will better predict the diuretic need and long-term outcomes (all cause mortality, all cause rehospitalization, emergency department visits) compared to standard evaluation.

Eligibility

Min Age: 18 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying whether using real-time ultrasound measurements of vein pressure (PVP — peripheral venous pressure) to guide fluid removal can improve outcomes in people hospitalized for heart failure. **You may be eligible if...** - You are 18–99 years old - You have been admitted to the hospital for heart failure (either new-onset or worsening of chronic heart failure) - You have agreed to participate **You may NOT be eligible if...** - You have a history of upper arm vein disease - Your kidney function is severely reduced (creatinine 3.5 mg/dL or higher) - You have severe heart valve disease or hypertrophic obstructive cardiomyopathy - You have a left ventricular assist device or have had a heart transplant - You have cardiogenic shock - You have a permanent central venous catheter Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDiuretic therapy

Diuretic therapy will be tailored according to peripheral venous pressure targets or standard approach

Locations(16)

Ankara Etlik City Hospital

Ankara, Turkey (Türkiye)

Antalya Atatürk State Hospital

Antalya, Turkey (Türkiye)

Akdeniz University

Antalya, Turkey (Türkiye)

Trakya University

Edirne, Turkey (Türkiye)

Erzurum Atatürk University Hospital

Erzurum, Turkey (Türkiye)

Eskişehir City Hospital

Eskişehir, Turkey (Türkiye)

Mehmet Akif Ersoy Training and Research Hospital

Istanbul, Turkey (Türkiye)

Basaksehir Cam and Sakura City Hospital

Istanbul, Turkey (Türkiye)

Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital

Istanbul, Turkey (Türkiye)

Bağcılar Training and Research Hospital

Istanbul, Turkey (Türkiye)

Bakırçay University, Faculty of Medicine

Izmir, Turkey (Türkiye)

Pazarcık State Hospital

Kahramanmaraş, Turkey (Türkiye)

Kafkas University Health Research and Application Hospital

Kars, Turkey (Türkiye)

Kütahya Health Sciences University

Kütahya, Turkey (Türkiye)

İdil State Hospital

Şırnak, Turkey (Türkiye)

Tokat Gaziosmanpaşa University

Tokat Province, Turkey (Türkiye)

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NCT06495892

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