RecruitingPhase 4NCT06501443

LATAM LOWERS LDL-C

Latin America Lipid Optimization After Acute Event in Patients With AthErosclerotic CardiovasculaR DiseaSe and High LDL-C


Sponsor

Novartis Pharmaceuticals

Enrollment

520 participants

Start Date

Feb 11, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is an open label, patient-level 1:1 randomized clinical trial in a multi-country study aiming to evaluate the real-world impact of inclisiran + Usual Care (UC) vs UC alone on LDL-C lowering, patient-reported outcomes, and healthcare resource utilization in an in-hospital population of patients, admitted during the acute setting, stabilized and before discharge, following an acute cardiovascular event.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called KJX839 and a drug called Usual care for people with hypercholesterolaemia. The study is currently recruiting participants at 11 locations. People eligible for this study include aged 18 Years to 100 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGUsual care

Treatment after acute event approved in the country where patient is based. It may include educational intervention according to each country guidelines

DRUGKJX839

Inclisiran in solution for subcutaneous injection on day 1, day 90, and day 270


Locations(11)

Novartis Investigative Site

Corrientes, Argentina

Novartis Investigative Site

Salvador, Estado de Bahia, Brazil

Novartis Investigative Site

Belo Horizonte, Minas Gerais, Brazil

Novartis Investigative Site

Belo Horizonte, Minas Gerais, Brazil

Novartis Investigative Site

Campo Largo, Paraná, Brazil

Novartis Investigative Site

Porto Alegre, Rio Grande do Sul, Brazil

Novartis Investigative Site

Blumenau, Santa Catarina, Brazil

Novartis Investigative Site

São José, Santa Catarina, Brazil

Novartis Investigative Site

São José, São Paulo, Brazil

Novartis Investigative Site

Campina Gde Do Sul, Brazil

Novartis Investigative Site

Salvador, Brazil

View Full Details on ClinicalTrials.gov

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NCT06501443


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