RecruitingNCT06503380

Real-world Study on the Management of Hematological Toxicities Associated With Targeted Therapies for Breast Cancer


Sponsor

Fudan University

Enrollment

1,000 participants

Start Date

Jul 15, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This multicenter, real-world, observational study will retrospectively and prospectively collect real-world data related to the investigational drugs. We plan to observe 1000 patients and collect data on treatment cycles N and N+1 of the targeted therapies. Retrospective data collection is based on existing patient diagnosis and treatment records, collecting information on patients who have completed two treatment cycles before January 1, 2024. Prospective data collection is based on routine clinical treatment during the study period, collected until the end of the next cycle of treatment or early termination of the study. To observe the disease characteristics and management mode of hematological toxicity related to targeted therapies of breast cancer, and explore the possible related factors of hematological toxicity, such as age, disease subtype, cancer stage, targeted therapy regimens, etc. This study will respect the medication choices of researchers in the study, without specifying which medication to choose for treatment, dosage, mode of administration (including single drug, combination therapy, or sequential therapy), and duration of administration.


Eligibility

Plain Language Summary

Simplified for easier understanding

This is a real-world observational study looking at how doctors manage blood-related side effects (low red blood cells, low white blood cells, or low platelets) in breast cancer patients being treated with targeted therapies. **You may be eligible if...** - You have been diagnosed with any type of breast cancer - You are currently receiving or have completed targeted therapy for your breast cancer - Your doctor has determined you needed treatment or prevention for blood-related side effects (low counts) from targeted therapy - You have signed informed consent to participate **You may NOT be eligible if...** - You are pregnant or breastfeeding - You are unable to understand the study or provide informed consent - Your doctor has determined that participation is not appropriate for you Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERNo intervenrion.

This study will respect the medication choices of researchers in the study, without specifying which medication to choose for treatment, dosage, mode of administration (including single drug, combination therapy, or sequential therapy), and duration of administration.


Locations(1)

Zhi-Ming Shao

Shanghai, Not US/Canada, China

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NCT06503380


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