RecruitingNot ApplicableNCT06503666

Zambian Informed Motivated Aware Responsible Adolescent Girls and Adults


Sponsor

Centre for Infectious Disease Research in Zambia

Enrollment

1,200 participants

Start Date

Apr 7, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The proposed hybrid effectiveness-implementation study will systematically adapt the Informed, Motivated, Aware, Responsible Adolescent Girls and Adults (IMARA) curriculum that was previously adapted for South Africa (IMARA-SA) to use in Zambia (will be renamed Zambian Informed, Motivated, Aware, Responsible Adolescent Girls and Adults (ZAIMARA) and evaluate the impact of ZAIMARA on improving adolescent girls and young women HIV testing, HIV and STI incidence, PrEP uptake and sexual risk behaviour. The study will also assess the impact of monthly mental health screening with referral versus a monthly nutrition and exercise screening on peer leaders job retention. We will also examine implementation factors and outcomes associated with ZAIMARA across five sites.


Eligibility

Sex: FEMALEMin Age: 15 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study tests a program called IMARA-SA (Zambian Informed Motivated Aware Responsible Adolescents) designed to help teenage girls and young women in Zambia protect their sexual and reproductive health, with the involvement of mother figures and peer leaders. The goal is to reduce HIV risk and improve health knowledge and behaviors. **You may be eligible if...** - You are a girl or young woman aged 15–19, unmarried, not known to be living with HIV, and living outside the five study areas in Zambia - You speak Nyanja, Bemba, or English - As a mother figure: you are over 24, live with or see the young woman daily, and were chosen by her - As a peer leader: you are 22–29 years old (for youth sessions) or over 30 (for adult sessions), have at least a Grade 12 education, and have experience working with young people **You may NOT be eligible if...** - You are already enrolled in another sexual and reproductive health program - You are known to be living with HIV at the time of recruitment (though those who test positive at the baseline can still attend workshops and will be referred to care) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALZAIMARA

The ZAIMARA curriculum focuses on strengthening communication between adolescent girls and young women (AGYW) and their mother figures (MF) to make healthy sexual decisions, to learn more about HIV, sexually transmitted infections (STIs), and pre-exposure prophylaxis (PrEP). The topics in the curriculum focus on effective communication, mothers talking to daughters on sex, HIV, STIs and PrEP. The intervention consists of participants attending a two day workshops with their MF. Other names: ZAIMARA

BEHAVIORALHealth Promotion

The health promotion (HP) curriculum focuses on healthy living by encouraging good nutrition, improving knowledge on violence recognition, management and support/resources, exercise, informed consumer behavior, alcohol and substance use.The intervention consists of participants attending a two day workshops with their MF. Other names: HP


Locations(1)

Chainda, Matero, Chelston, Chongwe and Kalingalinga

Lusaka, Lusaka Province, Zambia

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NCT06503666


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