Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia
Prevalence of Dental Dyschromia and Impact on the Quality of Life of Participants With Prolonged Hyperbilirubinemia During Their Early Years
University Hospital, Toulouse
120 participants
Apr 7, 2026
OBSERVATIONAL
Conditions
Summary
The main objective of this study is to assess the prevalence of dental discoloration (dental dyschromia) in children who experienced high levels of bilirubin in their blood (hyperbilirubinemia) during their early years. The study will also examine risk factors associated with this condition, such as the duration and severity of hyperbilirubinemia, underlying diseases, and treatments received. The researchers hypothesize that the quality of life of individuals with dental dyschromia is lower than that of individuals without dyschromia. The results of this study will be used to discuss coverage for dental care with health insurance for children affected by this condition.
Eligibility
Inclusion Criteria2
- A patient with biliary atresia, progressive familial intrahepatic cholestasis, or Alagille syndrome
- Patient or legal representative not opposed to participating in this research.
Exclusion Criteria1
- Inability to understand and respond to quality of life questionnaires
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Interventions
* " Psychosocial Impact of Dental Aesthetics Questionnaire " PMID 24280547 * " Orofacial Esthetic Scale " PMID 30856637 * " Orofacial Esthetic Scale " PMID 34231057 * A photograph of the patient's smile will be sent to 2 dentists who will also assess the presence or absence of dental dyschromia.
Locations(9)
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NCT06506734