Induction Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer

This study is testing whether adding a drug called cadonilimab (an immunotherapy) to standard chemotherapy before radiation can improve outcomes for people with locally advanced cervical cancer. Cadonilimab helps the immune system recognize and attack cancer cells. **You may be eligible if...** - You have been diagnosed with cervical cancer (squamous cell, adenocarcinoma, or adenosquamous type) - Your cancer is stage IB3 through IVA (locally advanced, not yet spread to distant organs) - You are 18 years or older with good physical functioning (ECOG 0-2) - You have measurable disease on imaging - Your main organs are functioning well **You may NOT be eligible if...** - Your cervical cancer is a rare type such as neuroendocrine or sarcoma - Your cancer has spread to distant areas including lymph nodes above the L1 vertebra level - You have had your uterus and cervix completely removed (total hysterectomy) - You have active autoimmune disease or are on immunosuppressive therapy - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.