RecruitingNot ApplicableNCT06511934

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

Intuitive, Complete Neural Control of Tablet Computers for Communication


Sponsor

Leigh R. Hochberg, MD, PhD.

Enrollment

2 participants

Start Date

Jul 22, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

People with brainstem stroke, advanced amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), or other disorders can become unable to move or speak despite being awake and alert. In this project, the investigators seek to further translate knowledge about interpreting brain signals related to movement, and to further develop an intracortical brain-computer interface (iBCI) that could restore rapid and intuitive use of communication apps on tablet computers by people with paralysis.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria4

  • Clinical diagnosis of spinal cord injury, brainstem stroke, muscular dystrophy, amyotrophic lateral sclerosis or other motor neuron disorders
  • Complete or incomplete tetraplegia (quadriplegia)
  • Must live within a three-hour drive of the Study site
  • Prior enrollment in BrainGate2 clinical trial (NCT00912041)

Exclusion Criteria3

  • Visual impairment such that extended viewing of a computer monitor would be difficult even with ordinary corrective lenses
  • Chronic oral or intravenous steroids or immunosuppressive therapy
  • Other serious disease or disorder that could seriously affect ability to participate in the study

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Interventions

DEVICEBrainGate Neural Interface System

Placement of the BrainGate2 sensor(s) into arm-hand motor-related cortex.


Locations(1)

Masssachusetts General Hospital

Boston, Massachusetts, United States

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NCT06511934


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