tetraplegia Clinical Trials

39 recruitingLast updated: July 26, 2026

There are 39 actively recruiting tetraplegia clinical trials across 10 countries. Studies span Not Applicable, Early Phase 1, Phase 2, Phase 3. Top locations include Boston, Massachusetts, United States, New York, New York, United States, Baltimore, Maryland, United States. Updated daily from ClinicalTrials.gov.


tetraplegia Trials at a Glance

39 actively recruiting trials for tetraplegia are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 31 trials, with the heaviest enrollment activity in Boston, New York, and Baltimore. Lead sponsors running tetraplegia studies include Neuralink Corp, Leigh R. Hochberg, MD, PhD., and Wandercraft.

Browse tetraplegia trials by phase

Treatments under study

About tetraplegia Clinical Trials

Looking for clinical trials for tetraplegia? There are currently 20 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new tetraplegia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about tetraplegia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 39 trials

Recruiting
Not Applicable

Evaluation of an Advanced Lower Extremity Neuroprostheses

StrokeSpinal Cord InjuriesParalysis+2 more
Case Western Reserve University10 enrolled2 locationsNCT00623389
Recruiting
Not Applicable

Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)

Spinal Cord Injuries (SCI)Amyotrophic Lateral Sclerosis(ALS)Muscular Dystrophies+6 more
Johns Hopkins University5 enrolled1 locationNCT07521930
Recruiting
Not Applicable

Transspinal Stimulation With and Without Blood Flow Restricted Exercise Via Telehealth in Persons With Tetraplegia

Tetraplegia/Tetraparesis
Virginia Commonwealth University44 enrolled3 locationsNCT05423600
Recruiting
Not Applicable

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

ALSSpinal Cord InjuriesCervical Spinal Cord Injury+2 more
Leigh R. Hochberg, MD, PhD.6 enrolled1 locationNCT06511934
Recruiting
Early Phase 1

Spinal Cord Associative Plasticity Study

Cervical Spinal Cord InjuryCervical MyelopathyTetraplegia/Tetraparesis
Columbia University92 enrolled3 locationsNCT05163639
Recruiting
Not Applicable

Innovative Brain-Computer Interface for People With Spinal Cord Injury

QuadriplegiaSpinal Cord InjuryTetraplegia C1-C4
UMC Utrecht1 enrolled1 locationNCT07640711
Recruiting
Not Applicable

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

AnarthriaAmyotrophic Lateral SclerosisSpinal Cord Injuries+5 more
Leigh R. Hochberg, MD, PhD.3 enrolled2 locationsNCT05724173
Recruiting
Phase 2Phase 3

Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI)

Metabolic SyndromeSpinal Cord InjuryTraumatic Spinal Cord Injury+1 more
Northwell Health60 enrolled3 locationsNCT07625332
Recruiting
Not Applicable

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia

Amyotrophic Lateral SclerosisSpinal Cord Injurieslocked-in Syndrome+3 more
Leigh R. Hochberg, MD, PhD.27 enrolled6 locationsNCT00912041
Recruiting

Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury

Spinal Cord InjuryUpper Extremity ParesisSCI - Spinal Cord Injury+5 more
University of British Columbia40 enrolled4 locationsNCT05638191
Recruiting
Not Applicable

Cortical Recording and Stimulating Array Brain-Machine Interface

Spinal Cord InjuryBrainstem StrokeBrachial Plexus Injury+2 more
Michael Boninger30 enrolled2 locationsNCT01894802
Recruiting
Not Applicable

Development and Validation of a New Questionnaire for Caregivers to Assess Hip Pain in Quadriplegic Pediatric Patients: Non-Ambulatory Hip Pain Questionnaire

Quadriplegia/Tetraplegia
Azienda USL Reggio Emilia - IRCCS100 enrolled2 locationsNCT06798233
Recruiting
Not Applicable

Brain Controlled Spinal Cord Stimulation in Participants With Cervical Spinal Cord Injury for Upper Limb Rehabilitation

Cervical Spinal Cord Injurytetraplegia
Ecole Polytechnique Fédérale de Lausanne3 enrolled1 locationNCT05665998
Recruiting
Not Applicable

Self-balancing Personal Exoskeleton for SCI (WIP)

Spinal Cord InjuriesParaplegia and Tetraplegia
Wandercraft10 enrolled1 locationNCT07536386
Recruiting
Not Applicable

Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)

StrokeAmyotrophic Lateral SclerosisDysarthria+3 more
Paradromics2 enrolled3 locationsNCT07357428
Recruiting
Not Applicable

Virtual Peer Coaching in Manual Wheelchair Skills

Spinal Cord InjurySpinal Cord Injuries (SCI)Tetraplegia/Tetraparesis+2 more
University of Pittsburgh132 enrolled1 locationNCT06295146
Recruiting
Early Phase 1

MEP Up-conditioning to Target Corticospinal Plasticity

Spinal Cord InjuryTetraplegia/Tetraparesis
Medical University of South Carolina11 enrolled1 locationNCT06989905
Recruiting

Nerve Transfer to Improve Function in High Level Tetraplegia

Cervical Spinal Cord Injurytetraplegia
Washington University School of Medicine30 enrolled10 locationsNCT06288763
Recruiting
Not Applicable

MyHand-SCI: An Active Hand Orthosis for Spinal Cord Injury

Spinal Cord Injuriestetraplegia
Columbia University40 enrolled1 locationNCT05553457
Recruiting
Not Applicable

Self-balancing Personal Exoskeleton for SCI (WINY)

Spinal Cord InjuryParaplegia and Tetraplegia
Wandercraft12 enrolled1 locationNCT07222033