Role of Topical Steroid Injection With Refractory Benign Esophageal Stricture Endoscopic Dilatation in Children
Mohammad Daboos
21 participants
Mar 2, 2022
INTERVENTIONAL
Conditions
Summary
This clinical trial study included 21 children with refractory benign esophageal strictures. Upper GI endoscopy performed up to the area of stricture, esophageal dilatation done, endoscopy repeated, and steroid injected intralesional under direct endoscopic vision. The effect of the procedure was followed over a period of 12 months by evaluation of number of dilatation, maximum dilator size, periodic dilatation index (PDI) and dysphagia score.
Eligibility
Inclusion Criteria3
- Pediatric patients aged less than 14 years
- with refractory benign esophageal strictures
- received a dilatation therapy without triamcinolone injections
Exclusion Criteria3
- failure to pass a guide wire secondary to pharyngeal stenosis
- tracheo-esophageal fistula
- those who received triamcinolone injections at early dilatation
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Interventions
Under general anesthesia with the patient in the left lateral position. A single-channel endoscope was used. Endoscopic bougie dilatation was performed using Wire-guided Polyvinyl dilator Savary Gilliard/SG. Long-acting steroids triamcinolone acetonide was injected via 25-gauge sclerotherapy catheter. One mL solution of triamcinolone acetonide 40mg/ml was diluted with one mL of saline, in a 2 mL disposable syringe, and 0.5 mL each was injected at the proximal margin of the stricture in four quadrants, 2 mL solution in four quadrants
Locations(1)
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NCT06514079