RecruitingNot ApplicableNCT06514729
The Effects of Different Ventilation Modes on Patients With Pulmonary Lobe Resection
The Effects of Different Ventilation Modes on Patients With Plasma Inflammatory Factor and Respiratory Function in Patients With Pulmonary Lobe Resection
Sponsor
Mao Enting
Enrollment
102 participants
Start Date
Jan 1, 2024
Study Type
INTERVENTIONAL
Conditions
Summary
The objective of this study was to discuss the effects of different ventilation modes on patients with plasma inflammatory factor and respiratory function in patients with pulmonary removal.
Eligibility
Min Age: 18 YearsMax Age: 75 Years
Inclusion Criteria4
- Comprehensive examination and analysis of imaging, laboratory examination and other comprehensive examinations, the diagnosis is clear, which is in line with lobe resection surgical indications
- Age 18-75 years old, the gender is not limited;
- ASA grading Ⅰ ~ III level;
- It is expected that the single lung ventilation time is ≥1 hours, and ≤3 hours
Exclusion Criteria8
- Emergency surgery;
- There is a taboos on the existence of systemic anesthesia;
- There is a history of acute chronic upper respiratory infections in the past January;
- Previous bronchial asthma, chronic obstructive pulmonary disease, bronchial dilatation, phthisis ,aspergillosis , acute respiratory distress syndrome or history of respiratory failure;
- Merge the function of important organs such as heart, liver, and kidney;
- There was a history of chest surgery and the history of trauma;
- Preoperative lung function test obvious abnormal abnormal abnormalities (1 second of exhalation (FEV1) <60%);
- Patients refuse to participate in the clinical trial
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Interventions
PROCEDUREAdopting different ventilation modes during the operation
The ventilation side adopts different ventilation modes combined with continuous positive pressure ventilation on the surgical side.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06514729
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