Lung Injury Clinical Trials

43 recruitingLast updated: June 17, 2026

There are 43 actively recruiting lung injury clinical trials across 15 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1. Top locations include Toronto, Ontario, Canada, Guangzhou, Guangdong, China, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


Lung Injury Trials at a Glance

43 actively recruiting trials for lung injury are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 16 trials, with the heaviest enrollment activity in Toronto, Guangzhou, and Beijing. Lead sponsors running lung injury studies include University Health Network, Toronto, Medical University of Vienna, and Centre hospitalier de l'Université de Montréal (CHUM).

Browse lung injury trials by phase

Treatments under study

About Lung Injury Clinical Trials

Looking for clinical trials for Lung Injury? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Lung Injury trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Lung Injury clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 43 trials

Recruiting

Recovery of Physical Function After Critical Illness In Older Adults

SepsisAcute Lung Injury(ALI)
University of Kentucky150 enrolled1 locationNCT07225257
Recruiting
Not Applicable

Dynamic Compliance-Guided Ventilation in Lumbar Surgery

ventilator-induced lung injuryPostoperative ComplicationsLumbar Disc Herniation+1 more
Ankara City Hospital Bilkent72 enrolled1 locationNCT07349719
Recruiting

Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)

Lung InjuryCardiopulmonary Bypass
Sophia Koutsogiannaki56 enrolled1 locationNCT04296071
Recruiting
Phase 2Phase 3

Pirfenidone Capsules in the Treatment of Radiation-induced Lung Injury With or Without Immune Pneumonia

Radiation Induced Lung InjuryImmune-related Pneumonia
Beijing Continent Pharmaceutical Co, Ltd.298 enrolled36 locationsNCT07388680
Recruiting
Not Applicable

Incentive Spirometry to Improve Outcomes in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy

Non-small Cell Lung Cancer (NSCLC)Lung CancerRadiation Induced Lung Injury+2 more
The Cooper Health System100 enrolled1 locationNCT06688422
Recruiting
Not Applicable

Clinical Decision Support Tool in PARDS Pilot Study

ventilator-induced lung injuryARDSVentilation Therapy; Complications
Children's Hospital Los Angeles180 enrolled8 locationsNCT04068012
Recruiting
Phase 2

Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury

Lung CancerPancreas CancerRadiation Fibrosis+1 more
Massachusetts General Hospital72 enrolled1 locationNCT04485286
Recruiting
Not Applicable

Functional Lung Avoidance Radiotherapy Guided by 4DCT Pulmonary Ventilation Function Imaging: A Prospective Single-arm Clinical Study

Radiation PneumonitisRadiation Induced Lung InjuryLung Cancer (Including Metastatic Cancer)
The Second Affiliated Hospital of Chongqing Medical University100 enrolled1 locationNCT07339644
Recruiting
Not Applicable

Evaluation of the Efficacy of Diagnostic Support Algorithms in Chest X-rays- LuAna Trial

PneumothoraxPleural EffusionLung Injury+3 more
Hospital Israelita Albert Einstein1,470 enrolled1 locationNCT06686251
Recruiting
Not Applicable

Open Lung Protective Extubation Following General Anesthesia

ventilator-induced lung injuryAnesthesiaAtelectasis+2 more
Centre hospitalier de l'Université de Montréal (CHUM)270 enrolled4 locationsNCT06296173
Recruiting
Not Applicable

Inspiratory Effort-Targeted Pressure Support Ventilation (IT-PSV) Trial

ventilator-induced lung injuryCritical CareAcute Hypoxic Respiratory Failure
Capital Medical University619 enrolled1 locationNCT06526598
Recruiting
Phase 2

This Study is Assessing the Safety and Efficacy of Immune Inhibition as a Treatment to Prevent Primary Graft Dysfunction

Acute Lung Injury(ALI)Natural Killer Cell Mediated ImmunityPrimary Graft Dysfunction+1 more
University of California, San Francisco120 enrolled1 locationNCT06853223
Recruiting
Phase 2Phase 3

A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation

Acute Respiratory Distress Syndrome (ARDS)Acute Lung Injury(ALI)Sepsis Related Acute Lung Injury/Acute Respiratory Distress Syndrome
Shanghai University of Traditional Chinese Medicine60 enrolled1 locationNCT07342205
Recruiting

Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute Respiratory and Cardiac Failure

Acute Lung InjuryAcute Respiratory FailureExtracorporeal Membrane Oxygenation Complication+1 more
Xenios AG20 enrolled2 locationsNCT06750536
Recruiting
Phase 2Phase 3

Vadadustat for the Treatment of Nonintubated Acute Respiratory Distress Syndrome Due to Pathogen-Associated Lung Injury

Nonintubated Acute Respiratory Distress Syndrome (ARDS)Pathogen-associated Lung Injury
Bentley J. Bobrow1,100 enrolled1 locationNCT07086755
Recruiting

Complications of the Alveolar Opening Maneuver in Children on Mechanical Ventilation

ComplicationPositive End-expiratory Pressure (PEEP)Oxygenation Index+3 more
Hospital de Alta Complejidad en Red143 enrolled1 locationNCT07233304
Recruiting

A New Ultrasonographic Tool to Assess Pulmonary Strain in the ICU

ventilator-induced lung injuryMechanical Ventilation Complication
Centre hospitalier de l'Université de Montréal (CHUM)10 enrolled1 locationNCT03405779
Recruiting
Phase 2

Anti-CD14 Treatment With IC14 in Hospitalized ARDS Patients

Acute Lung InjuryAcute Respiratory Distress SyndromeAcute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)+1 more
Implicit Bioscience56 enrolled2 locationsNCT06513949
Recruiting
Phase 2

PirfenidoneVsPlacebo as Prophylaxis Against Acute Radiation-induced Lung Injury Following HFRT in Breast Cancer Patients

PreventionAcute Lung Injury
Fujian Medical University Union Hospital214 enrolled1 locationNCT05704166
Recruiting

Digital Early Warning System for Acute Lung Injury in Liver Surgery

MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis)Acute Lung Injury(ALI)Liver Cirrhosis+4 more
Beijing Tsinghua Chang Gung Hospital4,000 enrolled1 locationNCT07070362