RecruitingNot ApplicableNCT06517927

Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10


Sponsor

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Enrollment

142 participants

Start Date

May 3, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

To date, there are no methods for assessing the risk of oral developmental defects that could predict long-term adverse effects in childhood cancer survivors. Having such a method at our disposal would enable us to better assess the risk to develop those defects and will help us provide new prevention and treatment strategies to ensure a healthy oral development. The aims of this study are : * Assess the caries risk in childhood cancer survivors compared with a control group. * Assess the dental development defects risk in childhood cancer survivors compared with a control group.


Eligibility

Min Age: 12 YearsMax Age: 36 Years

Inclusion Criteria3

  • age below 10 at cancer diagnosis (for the CCS group).
  • Chemotherapy must have been used to treat the patient (For the CCS group).
  • The patient is 12 years old or older at the time of the follow-up appointment of the present study

Exclusion Criteria5

  • A patient who was diagnosed and treated after 10 years old.
  • Patient below 12 years old at time of study recruitment
  • Patients with syndrome or diseases that involve teeth impairment\*
  • Pregnant patient
  • Refusal or inaptitude to undergo dental and radiographic examination

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Interventions

DIAGNOSTIC_TESTClinical and radiographic dental examination

complete clinical oral examination + intra-oral and panoramic x-rays


Locations(1)

Cliniques universitaires Saint-Luc

Brussels, Belgium

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NCT06517927


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