RecruitingNCT06518473

Atopy and Frequency of Exacerbation in Chronic Obstructive Pulmonary Disease Patients

The Relation Between Atopy and Frequency of Exacerbation in Chronic Obstructive Pulmonary Disease Patients


Sponsor

Mansoura University Hospital

Enrollment

50 participants

Start Date

Jul 14, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, sputum production and/or exacerbations) due to abnormalities of airways (bronchitis, bronchiolitis) and/or alveoli (emphysema) that cause persistent, often progressive, airflow obstruction. The presence of non-fully reversible airflow obstruction (FEV1/FVC \< 0.7 post-bronchodilation) measured by spirometry confirms the diagnosis of COPD


Eligibility

Min Age: 40 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether having atopy (a tendency to develop allergic conditions like hay fever or eczema) affects how often people with COPD (chronic obstructive pulmonary disease, a progressive lung disease usually caused by smoking) experience flare-ups (exacerbations). Researchers want to understand if undetected allergies play a role in worsening COPD. **You may be eligible if...** - You are 40–70 years old - You have been diagnosed with COPD according to current international guidelines (GOLD 2024 criteria) **You may NOT be eligible if...** - You have a known allergic condition (such as asthma, hay fever, or eczema) that was diagnosed before enrolling - You have another chronic lung condition alongside COPD - You have other significant health conditions that significantly affect your breathing - You have had a respiratory infection or taken systemic steroids in the month before enrollment Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTSkin prick test

Skin Prick Test (SPT): Common allergens including pollen, dust mites, Pet dander and mold. Serum IgE Levels: Total IgE Peripheral blood eosinophil was defined as an eosinophil count ≥ 5%, Quality of Life Assessment: COPD Assessment Test (CAT)


Locations(1)

Mohamed AbdElmoniem

Al Mansurah, Egypt

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NCT06518473


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