Atopy and Frequency of Exacerbation in Chronic Obstructive Pulmonary Disease Patients
The Relation Between Atopy and Frequency of Exacerbation in Chronic Obstructive Pulmonary Disease Patients
Mansoura University Hospital
50 participants
Jul 14, 2024
OBSERVATIONAL
Conditions
Summary
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, sputum production and/or exacerbations) due to abnormalities of airways (bronchitis, bronchiolitis) and/or alveoli (emphysema) that cause persistent, often progressive, airflow obstruction. The presence of non-fully reversible airflow obstruction (FEV1/FVC \< 0.7 post-bronchodilation) measured by spirometry confirms the diagnosis of COPD
Eligibility
Inclusion Criteria1
- Adults aged 40-70 years diagnosed with COPD according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2024 criteria
Exclusion Criteria4
- Patients with known allergic diseases before enrollment
- Patients with associated other chronic respiratory disorders
- Patients with significant comorbidities that could influence respiratory function.
- Recent respiratory infections or use of systemic corticosteroids within the last month before enrollment.
Interventions
Skin Prick Test (SPT): Common allergens including pollen, dust mites, Pet dander and mold. Serum IgE Levels: Total IgE Peripheral blood eosinophil was defined as an eosinophil count ≥ 5%, Quality of Life Assessment: COPD Assessment Test (CAT)
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06518473