RecruitingNot ApplicableNCT06521099

A Novel Conditioning Approach to Counter Loneliness in Adults


Sponsor

Education University of Hong Kong

Enrollment

136 participants

Start Date

Aug 19, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to test the efficacy of a 6-session conditioning paradigm by investigating the conditioning-induced change in the socio-affective processing, loneliness, depressive symptoms, and neural correlates of lonely adults.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • No histories of learning impairment, major psychiatric disorders or neurological disorders other than depression
  • Normal intelligence
  • At least primary school education

Exclusion Criteria1

  • On medication or treatments within 2 weeks prior to the beginning of the study that would affect the individual's brain, cognitive and affective functions

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Interventions

BEHAVIORALEvaluative Conditioning with positive stimuli

In the pre-conditioning phase, participants will be exposed to pictures that vary in their emotional (negative, positive) and social (non-social, social) content. For each picture, they are required to indicate their immediate perceived valence (between negative to positive), degree of social motivation (between none to high) on Likert-scales. In the conditioning phase, emotional social pictures will be selected and paired with non-social positive stimuli for trials in random order, for 6 sessions across 3 weeks. In the post-conditioning phase, participants will be asked to evaluate the valence of the stimuli again similar to that in pre-conditioning phase.

BEHAVIORALConditioning with neutral stimuli

In the pre-conditioning phase, participants will be exposed to pictures that vary in their emotional (negative, positive) and social (non-social, social) content. For each picture, they are required to indicate their immediate perceived valence (between negative to positive), degree of social motivation (between none to high) on Likert-scales. In the conditioning phase, emotional social pictures will be selected and paired with with neutral non-social stimuli for trials in random order, for 6 sessions across 3 weeks. In the post-conditioning phase, participants will be asked to evaluate the valence of the stimuli again similar to that in pre-conditioning phase.


Locations(1)

The University of Hong Kong

Hong Kong, Hong Kong

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NCT06521099


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