Identification of Molecular Signatures of High-risk Oncogenic HPV and Study of Their Associations With the Presence of High-grade Lesions and/or Anal Cancer 10 Years After Inclusion in the ANRS IPERGAY Trial

This study is a follow-up research project looking at people who participated in the ANRS IPERGAY clinical trial, specifically tracking whether certain high-risk strains of HPV (human papillomavirus) are linked to the development of high-grade anal lesions or anal cancer 10 years later. **You may be eligible if...** - You were a participant in the original ANRS IPERGAY trial and were enrolled in its HPV sub-study - You have signed informed consent - You are covered by a social security health insurance plan **You may NOT be eligible if...** - You are under legal guardianship or curatorship - You receive state medical assistance (free healthcare) - You disagree with the use of data collected during your participation in the IPERGAY trial Talk to your doctor to see if this trial is right for you.