Trabeculopuncture as Predictive Test for the Success of Ab Interno Trabeculectomy

This study is testing whether a quick, minimally invasive procedure called trabeculopuncture can predict how well a more involved glaucoma surgery (ab interno trabeculectomy) will work to lower eye pressure. Glaucoma damages the optic nerve due to high eye pressure, and finding the right surgical approach is important for protecting vision. **You may be eligible if...** - You are 18 or older - You have primary open-angle glaucoma, pigmentary glaucoma, or pseudoexfoliation glaucoma - Your eye pressure cannot be adequately controlled with maximum tolerated eye drop medications - Your vision tests show your glaucoma is worsening (progressive nerve fiber thinning and visual field loss) - You also have a visually significant cataract that needs to be addressed **You may NOT be eligible if...** - You have neovascular, angle-closure, or uveitic glaucoma - You have previously had glaucoma surgery - You have conditions affecting the veins around your eye (such as Graves' disease, Sturge-Weber syndrome, or arteriovenous fistulas) Talk to your doctor to see if this trial is right for you.