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RecruitingNot ApplicableNCT06523751

Trabeculopuncture as Predictive Test for the Success of Ab Interno Trabeculectomy

Determining Distal Outflow Tract Function in Open Angle Glaucoma as a Predictive Test for the Success of Ab Interno Trabeculectomy

Sponsor

Wuerzburg University Hospital

Enrollment

55 participants

Start Date

Jun 13, 2023

Study Type

INTERVENTIONAL

Conditions

Open Angle GlaucomaPseudoexfoliation Glaucoma

Summary

The purpose of this study is to perform trabeculopuncture a test to determine the distal outflow tract function to predict the success of ab interno trabeculectomy.

Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • individuals ≥ 18 years of age
  • clinical diagnosis of: primary open angle glaucoma, pigmentary glaucoma, or pseudoexfoliation glaucoma
  • uncontrolled intraocular pressure (IOP) with maximally tolerated medical therapy
  • progressive thinning of retinal nerve fiber layer assessed by Spectral domain optical coherence tomography (p \< 0.05)
  • progression of visual field defects
  • visually significant cataract and indication to reduce IOP or glaucoma medication burden

Exclusion Criteria3

  • clinical diagnosis of neovascular glaucoma, angle-closure glaucoma, uveitic glaucoma, neovascular glaucoma
  • prior glaucoma surgery
  • preexisting conditions affecting the episcleral venous pressure including Grave's ophthalmopathy, Sturge-Weber syndrome, Arteriovenous fistulas (carotid-cavernous fistula)

Interventions

DIAGNOSTIC_TESTTrabeculopuncture

Trabeculopuncture is performed with a Nd:YAG laser on the trabecular meshwork. Four punctures are created along the 180° nasal trabecular meshwork.

Locations(1)

Uniklinikum Würzburg

Würzburg, Bavaria, Germany

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NCT06523751

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