Open Angle Glaucoma Clinical Trials

17 recruiting

Frequently Asked Questions

Common questions about Open Angle Glaucoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 48 trials

Recruiting

Quality of Life After Glaucoma Surgery: Evaluating the Patient Perspective Across Surgical Options

Open Angle GlaucomaGlaucoma EyeClosed-Angle Glaucoma+2 more
Hospices Civils de Lyon132 enrolled1 locationNCT07303257
Recruiting
Not Applicable

Transcorneal Electrical Stimulation for the Treatment of Visual Field Defects in Patients With Open-Angle Glaucoma

GlaucomaPrimary Open Angle GlaucomaPseudoexfoliation Glaucoma+2 more
Okuvision GmbH50 enrolled1 locationNCT06682962
Recruiting
Not Applicable

Aqueous Humor and Ocular Tissue Analysis in Glaucoma and Cataract

CataractPrimary Open Angle Glaucoma (POAG)
Military Institute od Medicine National Research Institute40 enrolled2 locationsNCT07462000
Recruiting

UBM Evaluation After Combined Deep Sclerectomy With Trabeculotomy in Primary Open Angle Glaucoma

Primary Open Angle Glaucoma (POAG)
Minia University Hospital30 enrolled1 locationNCT07454447
Recruiting
Phase 4

Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

Open Angle GlaucomaGlaucomaOcular Hypertension+1 more
University of Miami20 enrolled1 locationNCT07217678
Recruiting
Not Applicable

Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea

ObesityObstructive Sleep ApneaPrimary Open Angle Glaucoma
Cairo University40 enrolled1 locationNCT07447011
Recruiting
Phase 3

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Primary Open Angle Glaucoma
AbbVie130 enrolled21 locationsNCT06822738
Recruiting
Phase 4

Supplementary Kelulut Honey Therapy in Juvenile Open-Angle Glaucoma: Effects on IL-6, RNFL and Dry Eye

Juvenile Open Angle GlaucomaDry Eye Disease (DED)Interleukin 6+2 more
Universiti Sains Malaysia60 enrolled4 locationsNCT07396441
Recruiting

DSLT for Reducing Medication in Glaucoma

Ocular HypertensionPrimary Open Angle Glaucoma
The Eye Institute of West Florida60 enrolled1 locationNCT07390890
Recruiting
Not Applicable

Clinical Study Evaluating the Safety and Performance of the MIST Device for Intraocular Pressure Reduction in Patients With Primary Open-Angle Glaucoma

Primary Open Angle Glaucoma
Hexiris Inc25 enrolled5 locationsNCT07358650
Recruiting
Not Applicable

Evaluation of BRUDYGLAUCO (DHA + Citicoline) in Patients With Glaucoma

GlaucomaPrimary Open Angle Glaucoma (POAG)Neuroprotection
Institut Catala de Retina108 enrolled2 locationsNCT07322965
Recruiting
Not Applicable

OMNI 3.1 Surgical System in Subjects With Primary Open-Angle Glaucoma

Primary Open Angle Glaucoma
Sight Sciences, Inc.25 enrolled1 locationNCT06991270
Recruiting
Phase 3

Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular HypertensionPrimary Open Angle Glaucoma (POAG)
Huons Co., Ltd.206 enrolled1 locationNCT07335211
Recruiting
Not Applicable

A Comparative Study of Intraocular Pressure Control Using Selective Laser Trabeculoplasty and Latanoprost as Initial Treatments for Primary Open Angle Glaucoma and Ocular Hypertension in Lagos State University Teaching Hospital

Primary Open Angle Glaucoma or Ocular Hypertension
Lagos State Health Service Commission138 enrolled1 locationNCT07310719
Recruiting
Not Applicable

Direct Selective Laser Trabeculoplasty in Ethnic Chinese Population

Ocular HypertensionPrimary Open Angle GlaucomaNormal Tension Glaucoma
BelkinVision45 enrolled2 locationsNCT05902871
Recruiting

Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle Glaucoma

GlaucomaPrimary Open Angle Glaucoma
Fondation Ophtalmologique Adolphe de Rothschild100 enrolled1 locationNCT05264818
Recruiting
Phase 1Phase 2

AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension

Open Angle GlaucomaOcular Hypertension
AbbVie96 enrolled49 locationsNCT04499248
Recruiting
Not Applicable

Comparative Effectiveness and Safety of ELIOS in Patients With Open-Angle Glaucoma Undergoing Cataract Surgery

Open Angle Glaucoma
Elios Vision, Inc.194 enrolled16 locationsNCT06246136
Recruiting
Phase 4

A Study to Evaluate Adverse Events and Change in Disease Activity With the XEN45 Glaucoma Treatment System Implantation In Adult Participants With Open-Angle Glaucoma in China

Open Angle GlaucomaOAG
AbbVie130 enrolled13 locationsNCT05821855
Recruiting
Phase 4

Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma

Open Angle GlaucomaPseudoexfoliation GlaucomaPigmentary Glaucoma
Jonathon Myers20 enrolled1 locationNCT07228221