RecruitingNot ApplicableNCT06529120

Adaptation and Pilot Testing of a Mindfulness-Based Insomnia and Symptom Management Intervention for Women With Breast Cancer Receiving Treatment in Rural Medically Underserved Areas


Sponsor

Duke University

Enrollment

15 participants

Start Date

Sep 11, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Women with breast cancer often experience multiple difficult symptoms, for example insomnia, fatigue, stress, and pain. This study is being done to test a mindfulness-based insomnia and symptom management intervention for women with breast cancer (Nite2Day). Participants will complete six, 45-60 minute intervention sessions with a study therapist. Intervention sessions will be conducted remotely via conference (i.e., Zoom) or telephone. During these sessions, participants will learn mindfulness and cognitive-behavioral strategies to cope with nighttime sleep disturbances and daytime symptoms of fatigue, stress, and pain. Participants will be asked to complete three, brief (15-20 minute) surveys that will ask questions about their background, cancer diagnosis and treatments, cancer symptoms, and experience with the intervention. Participants will be compensated for completing all intervention sessions and surveys. Total study duration is about 12 weeks. The greatest risk of this study is loss of confidentiality. Benefits from participating might include learning skills to reduce nighttime sleep disturbances and daytime symptoms of fatigue, stress, and pain. Information learned from this study may also benefit other patients with cancer in the future.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria5

  • stage 0-IV breast cancer diagnosis within past 12 months
  • self-report \>8 on the Insomnia Severity Index, indicating at least mild symptoms of clinical insomnia
  • \>18 years old
  • life expectancy of \>12 months per medical chart or oncologist
  • Ability to speak and read English, and intact hearing and vision

Exclusion Criteria3

  • reported or suspected cognitive impairment confirmed via Folstein Mini-Mental Status Exam \<25;
  • serious psychiatric (e.g., schizophrenia, suicidal intent) or medical condition (e.g., seizure disorder, narcolepsy, severe or moderate untreated sleep apnea) indicated by self-report, medical chart, or oncologist/provider that would contraindicate safe participation;
  • engagement in behavioral insomnia (e.g., Cognitive-Behavioral Therapy for Insomnia) or symptom management (e.g., Pain Coping Skills Training) interventions within past 6 months

Interventions

BEHAVIORALMindfulness-Based Therapy for Insomnia with Cognitive-Behavioral Symptom Coping Skills

Mindfulness-based sleep strategies and cognitive-behavioral symptom coping skills.


Locations(4)

Calvert Health System

Prince Frederick, Maryland, United States

Duke Lifepoint Hospital Maria Parham Medical Center

Henderson, North Carolina, United States

Scotland Health Care System

Laurinburg, North Carolina, United States

UNC Health Johnston

Smithfield, North Carolina, United States

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NCT06529120


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