RecruitingNot ApplicableNCT06532747

Redefining BMI: The Body, Mind, and Inflammation Trial

Sponsor

Virginia Commonwealth University

Enrollment

32 participants

Start Date

Sep 26, 2025

Study Type

INTERVENTIONAL

Conditions

Obesity Adiposity

Summary

Emerging adulthood (18-25 years of age) is a critical developmental window to promote weight management and cardiometabolic health, particularly for emerging adult women. The primary purpose of this study is to test the preliminary efficacy of the intensive lifestyle intervention for EA women in reducing adiposity, as well as improving biomarkers of inflammation and metabolic risk over 12 months compared with a traditional behavioral weight loss intervention. This treatment program will be tested in emerging adult (EA) women ages 18-25 years old with a BMI of 25-50 kg/m\^2.

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 25 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Integrated Lifestyle Intervention (ILI) and a behavioral approach called Monitoring with digital tools for people with adiposity and obesity. The study is currently recruiting participants at 1 location. People eligible for this study include aged {"Not Applicable"} to 18 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BEHAVIORALIntegrated Lifestyle Intervention (ILI)

ILI participants will receive training in empirically supported strategies to improve psychological function (e.g., restructuring negative thoughts, distress tolerance), with a focus on changing discrete behaviors linked to inflammation (e.g., sleep, processed foods, physical activity), all intertwined with BWL content adapted to meet the needs of EAs.

BEHAVIORALMonitoring with digital tools

All participants will receive digital tools to facilitate self-monitoring-the initial 4-month program will consist of group sessions via Zoom (8 weekly, 4 bi-weekly) with weekly tailored e-coaching, followed by monthly boosters through 12 months.