RecruitingNot ApplicableNCT06538415

Adding Polyphenol-rich Pulses to Daily Diet Improves Skin Health by Reshaping the Skin Microbiome

To Determine Whether Adding Polyphenol-rich Pulses to Daily Diet Improves Skin Health by Reshaping the Skin Microbiome and Lipids, and Reducing Oxidative Stress and Inflammation in Women

Sponsor

University of Florida

Enrollment

50 participants

Start Date

Apr 24, 2026

Study Type

INTERVENTIONAL

Conditions

Healthy

Summary

Skin health is influenced by the microbiome, lipids, oxidative stress, inflammation, and UV exposure. A 12-week trial with 48 women aged 45-65 will test if polyphenol-rich pulses improve skin health by affecting these factors. Using a white rice control diet, the study will measure skin parameters and analyze correlations with changes in lipids and microbiome, potentially proving the benefits of pulses.

Eligibility

Sex: FEMALEMin Age: 45 YearsMax Age: 65 Years

Inclusion Criteria3

BMI (18.5-29.9)
Body weight ≥110 pounds
Fitzpatrick skin type 1,2 and 3.

Exclusion Criteria8

pregnancy
breast-feeding
impaired fasting glucose
frequent alcohol use
history of skin cancer
sunbathing and the use of tanning bed, intake of vitamin/mineral supplements
habitual high intake of fruits (≥ 2 cups daily)
intake of medication that might influence the outcome of the study

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Interventions

OTHERPulse Diet

Participants will consume cooked pulses on an alternating basis over the 10-week intervention period. The pulses consist of 455 grams of the tri-bean blend (kidney, pinto, black bean), equivalent to 350 calories, and 225 grams of black lentils (400 calories).

OTHERControl Rice Diet

Participants will consume cooked white rice (375 calories) over 10 weeks