RecruitingNCT06539104

Aftificial Inteligence in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy

Scanning the Meiotic Spindle in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy Evaluated by Artificial Intelligence (SMARTAI Study)


Sponsor

Charles University, Czech Republic

Enrollment

1,000 participants

Start Date

Jan 5, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The assisted reproduction success rate is affected by several factors including the age of the women, oocyte quality and maturation state, as well as sperm quality. Imaging of the meiotic spindle may be crucial for determining the oocyte maturation. Artificial intelligence (AI) will be applied to establish the complex oocyte quality, embryo ploidy and pregnancy success probability from the sequence of data, starting with the recording of the meiotic spindle in polarized light, through paternal factors up to the time lapse recording of early embryo development. This strategy should reduce the cost of fertility treatment thanks to increased efficiency in choosing the most promising candidates and reducing the need for costly laboratory analyses.


Eligibility

Min Age: 18 YearsMax Age: 49 Years

Inclusion Criteria4

  • Intracytoplasmatic Sperm Injection
  • Preimplantation genetic testing
  • Time lapse embryo record
  • Singned informed consent

Exclusion Criteria2

  • Gynecological diseases
  • Genetical diseases of parents

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREarteficial inteligence evaluation of oocyte and embryo development

apply AI to find out the complex oocyte quality, embryo development, embryo ploidy and pregnancy success probability from the sequence of the data starting from the recording of the meiotic spindle in polarized light, through paternal factors up to the time lapse record of early embryo development.


Locations(4)

General University Hospital in Prague

Prague, Czechia

Czech Technical University in Prague

Prague, Czechia

Institute of Physics AS CR

Prague, Czechia

Biocev As Cr

Vestec, Czechia

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06539104


Related Trials