RecruitingPhase 2NCT06686537

Convergent Mechanisms Underlying Reprometabolic Syndrome in Women

Convergent Mechanisms Underlying Reprometabolic Syndrome in Women and Sheep


Sponsor

University of Colorado, Denver

Enrollment

20 participants

Start Date

Feb 25, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Dr. Nanette Santoro proposes to test the specific question that obesity results in abnormal estradiol response at the level of the pituitary and hypothalamus. This will be shown in diminished pituitary sensitivity to gonadorelin releasing hormone with a reduced estradiol induced luteinizing hormone surge in obese women.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 38 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Estradiol Patches for people with infertility, female and obesity. The study is currently recruiting participants at 2 locations. People eligible for this study include women aged 18 Years to 38 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGEstradiol Patches

Estradiol patched will be worn for 7 days.


Locations(2)

University of Colorado School of Medicine

Aurora, Colorado, United States

University of Colorado-School of Medicine

Aurora, Colorado, United States

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NCT06686537


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