Convergent Mechanisms Underlying Reprometabolic Syndrome in Women
Convergent Mechanisms Underlying Reprometabolic Syndrome in Women and Sheep
University of Colorado, Denver
20 participants
Feb 25, 2025
INTERVENTIONAL
Conditions
Summary
Dr. Nanette Santoro proposes to test the specific question that obesity results in abnormal estradiol response at the level of the pituitary and hypothalamus. This will be shown in diminished pituitary sensitivity to gonadorelin releasing hormone with a reduced estradiol induced luteinizing hormone surge in obese women.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
Estradiol patched will be worn for 7 days.
Locations(2)
View Full Details on ClinicalTrials.gov
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NCT06686537