RecruitingNot ApplicableNCT06541028

Reducing Stigma in People Who Inject Drugs (PWID) With HIV Using a Rapid Start Antiretroviral Therapy Intervention (ART)

Reducing Stigma in People Who Inject Drugs With HIV Using a Rapid Start Antiretroviral Therapy Intervention (RS-ART)


Sponsor

Yale University

Enrollment

135 participants

Start Date

Nov 4, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study seeks to develop an RS-ART implementation strategy by utilizing the Delphi method and interviewing experts and PWID regarding their experiences with ART. This strategy will then be pilot tested in a randomized controlled trial (Aim 3). The research will not impact the type of medication and dose prescribed, but rather, how soon providers are able to prescribe ART after diagnosis. The focus of this registration is Aim 3.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether starting HIV antiretroviral therapy (ART) very quickly — on the same day or within a few days of diagnosis — helps reduce the stigma experienced by people who inject drugs (PWID) and improves their likelihood of staying on treatment. It is being conducted in HIV clinics and prison settings. **You may be eligible if...** - You are a person who injects drugs (including opioids, amphetamines, or other substances) who is newly enrolled in HIV treatment at a participating clinic - You are an HIV clinician who prescribes ART at a study clinic and are willing to use the rapid-start protocol - You may be from either the general population or a prison population **You may NOT be eligible if...** - You are a minor (under 18) and are an HIV clinician participant - You are unwilling to provide informed consent - You do not inject drugs (for the patient participant role) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALRapid-Start ART (RS-ART)

ART initiation within 7 days of HIV diagnosis. (RS-ART intervention to be informed and developed in Aims 1 and 2.) RS-ART is a strategy that focuses on clinical decision-making generally based solely on clinical criteria, and later organizing support for mental health, adherence, and management of comorbid conditions only after the patient has initiated ART.


Locations(3)

Kajang Prison

Kajang, Malaysia

Centre of Excellence for Research in AIDS (CERiA) - University of Malaya

Kuala Lumpur, Malaysia

Primary Healthcare Centers

Kuala Lumpur, Malaysia

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NCT06541028


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