RecruitingNCT06542016

An Evaluation of the KCCQ Score in Predicting Cardiovascular Risk in Dialysis Patients

A Prospective Study on Predicting Cardiovascular Events and Mortality Risk in Maintenance Dialysis Patients Based on Changes in KCCQ Scores


Sponsor

Shenzhen Second People's Hospital

Enrollment

136 participants

Start Date

Jul 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Cardiovascular Disease (CVD) is the main complication and the most important cause of death in CKD patients. As the disease progresses, the incidence of cardiovascular disease in CKD patients gradually increases, especially in End-Stage Renal Disease (ESRD) patients receiving dialysis treatment, where the prevalence of cardiovascular disease reaches its highest level. Currently, there is a lack of a simple and reliable tool to assess the cardiac function status and predict the risk of cardiovascular events in patients on maintenance dialysis. The Kansas City Cardiomyopathy Questionnaire (KCCQ) is a widely used patient-reported outcomes measurement tool for assessing health-related quality of life in heart failure patients. It has been shown that KCCQ scores not only reflect the underlying undiagnosed symptoms of heart failure in CKD patients, but also have a strong correlation with prognosis. However, there is currently insufficient clinical evidence to confirm the value of the KCCQ in patients on maintenance dialysis. Investigators will perform a prospective, single-center, observational study to collect the changing trend of KCCQ scores at baseline and during the observation periods in maintenance dialysis patients, to analyze the association between the scores and the occurrence of long-term cardiovascular events and all-cause mortality. The aim is to construct a predictive model of KCCQ scores to provide a reference basis for clinical management of this high-risk group, so as to optimize the diagnosis and treatment of heart failure in dialysis patients and improve their cardiovascular outcomes.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating whether a heart health questionnaire called the KCCQ (Kansas City Cardiomyopathy Questionnaire) can predict which dialysis patients are at higher risk for serious heart problems. Dialysis patients (people with end-stage kidney disease) have very high rates of heart disease, and a simple questionnaire tool that identifies high-risk individuals could help target care more effectively. **You may be eligible if...** - You are 18 or older with end-stage kidney disease (CKD stage 5) requiring dialysis (either hemodialysis or peritoneal dialysis) - You are either newly starting dialysis or already on regular dialysis - You can complete the KCCQ questionnaire and be contacted for follow-up **You may NOT be eligible if...** - You have acute kidney injury (not chronic kidney failure) - You have other serious conditions that make completing the questionnaire or follow-up unrealistic Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

First Shenzhen

Guangdong, Guangdong, China

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NCT06542016


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