IRONHEART: Intravenous Iron in Non-ischaemic Heart Failure

This study (called IRONHEART) is testing whether giving iron through an IV drip can help people with a specific type of heart failure. Their heart is weakened not from a blocked artery but from another cause, and they also have low iron levels. **You may be eligible if...** - You are 18 or older and have heart failure with a weakened pumping ability (ejection fraction below 40%) - Your heart failure is not caused by blocked arteries (non-ischaemic) - You have low iron levels (transferrin saturation below 20%) - You have been on standard heart failure medications, including an SGLT2 inhibitor, for at least 4 weeks - Your heart failure symptoms are mild to moderate (NYHA Class I–III) **You may NOT be eligible if...** - Your heart failure is caused by blocked arteries - You have severe kidney disease (eGFR below 30) or need dialysis - You have atrial fibrillation or atrial flutter - Your symptoms are severely limiting (NYHA Class IV) Talk to your doctor to see if this trial is right for you.