RecruitingNot ApplicableNCT06543407

Harm Reduction for Smokers With Mental Illness

Harm Reduction for Smokers With Mental Illness: RCT of E-cigarette Provision With or Without Behavioral Support to Boost Switching


Sponsor

Dartmouth-Hitchcock Medical Center

Enrollment

250 participants

Start Date

Oct 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

To compare the efficacy of e-cigarette (e-cig) provision with or without behavioral support (SWITCH IT) delivered via telehealth to reduce harm among smokers with MI who cannot quit smoking and are not ready to pursue cessation treatment, and to examine self-regulation (using e-cigs instead of cigarettes to cope with stress/distress and self-efficacy) as a potential mechanism for behavior change from SWITCH IT


Eligibility

Min Age: 21 Years

Inclusion Criteria11

  • Diagnostic Criteria (must have one to be eligible):
  • Schizophrenia
  • Bipolar disorder
  • Major Depressive Disorders
  • Posttraumatic disorder
  • Other anxiety disorders
  • years or older;
  • English-speaking;
  • Daily smoker (at least 10 cigarettes/day);
  • At least one quit attempt in the past 5 years using evidence- based pharmacotherapy or behavioral cessation support;
  • Not currently interested in quitting.

Exclusion Criteria10

  • Currently residing in a nursing home;
  • Current diagnosis of Asthma;
  • Cognitive impairment (score <26 on the Telephone Interview for Cognitive Status (TICS);
  • Current use of e-cigarettes (>once a week);
  • Psychiatric instability (hospitalized in the past month);
  • Current AND moderate to severe substance use disorder;
  • Pregnant or planning to become pregnant;
  • Use of any smoked products other than cigarettes;
  • Current unstable medical illness making e-cigarette unsafe (e.g., recent heart attack, cancer);
  • Participation in SWITCH IT pilot study.

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Interventions

BEHAVIORALSWITCH IT

Behavioral support for switching, 7-10 sessions with SWITCH IT coach delivered during the first 8 weeks of the study. SWITCH IT participants will also have the opportunity to receive supported "field trips" to explore e-cigarette options based on availability, cost, and preferences during week 4 and week 6.

OTHERE-cig Provision Only

Provision of e-cigarettes (NJOY) based on combusible use for the first 8 weeks of the study.


Locations(2)

Seven Counties Services

Louisville, Kentucky, United States

The Providence Center

Providence, Rhode Island, United States

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NCT06543407


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