RecruitingPhase 3NCT07059377

Semaglutide for Smoking Cessation in Patients With Diabetes

Semaglutide for Smoking Cessation in Patients With Diabetes: A Pilot Randomized Controlled Trial


Sponsor

Ottawa Heart Institute Research Corporation

Enrollment

100 participants

Start Date

Feb 13, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

To assess the feasibility of conducting a randomized controlled trial (RCT) to determine the effectiveness of semaglutide as an adjunct to combination NRT in supporting smoking cessation for patients with diabetes.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Nicotine replacement and a drug called Semaglutide for people with diabetes mellitus, type 2, nicotine addiction, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSemaglutide

Starting dose will be 0.25mg once a week for 4 weeks, then titrated up to 0.5mg once a week. For those requiring additional blood sugar control, the dose may be titrated up to the maximum dose of 2mg once a week. All participants will use this medication for up to 26 weeks

DRUGNicotine replacement

Nicotine patch plus short-acting NRT gum or lozenge


Locations(1)

University of Ottawa Heart Institute

Ottawa, Ontario, Canada

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NCT07059377


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