Multimodal Prognostic Assessment of Acute Ischemic Stroke Patients With Atrial Fibrillation: a Prospective, Multicenter, Observational Study (IAT-CLOSURE)

This observational study is tracking patients who had an ischemic stroke (a stroke caused by a blood clot) and also have atrial fibrillation (an irregular heartbeat). Researchers want to better understand the long-term risks these patients face — particularly the risk of the stroke coming back — and whether closing a small pouch in the heart called the left atrial appendage might help prevent future strokes. No experimental treatment is involved; the study collects data and follows patients over time. **You may be eligible if...** - You are over 18 years old - You had an ischemic stroke within the past 14 days - You have been diagnosed with atrial fibrillation (either before or during this hospitalization) - You or your legal representative are able to provide informed consent **You may NOT be eligible if...** - You have a pacemaker, defibrillator, or cardiac monitor implanted - The left atrial appendage has already been removed or blocked - Your atrial fibrillation is caused by a temporary reversible condition - You are pregnant or breastfeeding - You are unable to attend follow-up visits (e.g., no fixed address, living overseas) - You have a life expectancy of less than 1 year Talk to your doctor to see if this trial is right for you.