RecruitingNCT06550310

Nutrition and Clinical Outcomes in IBD

Nutrition and Body Composition and Association With Clinical Outcomes in Inflammatory Bowel Disease


Sponsor

Barts & The London NHS Trust

Enrollment

300 participants

Start Date

Oct 24, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to demonstrate that nutritional status and body composition have an impact on clinical outcomes in inflammatory bowel disease (IBD). The main objectives are: 1. To compare the detection rates of undernutrition between a range of nutritional screening tools, physiological measures and assessment tools amongst patients with different IBD phenotypes 2. To correlate nutritional status, nutritional biomarkers and body composition with clinical outcomes in patients with IBD treated with advanced medical therapy or surgery 3. To determine a potential relationship between radiological muscle mass measurements and clinical outcomes in patients with IBD treated with advanced medical therapy or surgery Participants will undergo an assessment at pre-treatment baseline and then again at their scheduled follow-up. This is a non-interventional study and participants will not be required to have any invasive tests or hospital visits beyond that of standard clinical care.


Eligibility

Min Age: 16 Years

Plain Language Summary

Simplified for easier understanding

This observational study is looking at how nutrition affects outcomes in patients with inflammatory bowel disease (IBD) — either Crohn's disease, ulcerative colitis, or IBD-unclassified — who are starting a new advanced medication or having IBD-related surgery. The goal is to understand whether better nutritional status leads to better treatment responses and recovery. **You may be eligible if...** - You are over 16 years old - You have been diagnosed with IBD (Crohn's disease, ulcerative colitis, or IBD-unclassified) - You are starting a new advanced medical therapy for IBD, OR - You are about to undergo IBD-related surgery - You are able and willing to provide informed consent **You may NOT be eligible if...** - You are under 16 years old - You are unable to provide informed consent - You have a cardiac pacemaker or internal defibrillator - You have active cancer or another condition associated with severe muscle wasting (cachexia) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Barts Health NHS Trust

London, United Kingdom

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NCT06550310


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