RecruitingNot ApplicableNCT06553053

Acupuncture Reduces Relapse in Patients With Crohn's Disease: a Superiority Trial

Sponsor

Shanghai Institute of Acupuncture, Moxibustion and Meridian

Enrollment

106 participants

Start Date

Aug 13, 2024

Study Type

INTERVENTIONAL

Conditions

Inflammatory Bowel Diseases Crohn's Disease Relapse

Summary

The aim of this study was to further improve the clinical efficacy of acupuncture in delaying the clinical recurrence of CD and to explore the efficacy mechanism of acupuncture efficacy enhancement.

Eligibility

Min Age: 16 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing whether acupuncture can reduce disease flares (relapses) in people with Crohn's disease — a chronic inflammatory bowel condition — who are currently in remission but have a history of frequent flares. It is designed as a superiority trial, meaning researchers believe acupuncture may work better than standard care alone. **You may be eligible if...** - You are 16–75 years old with a clinical diagnosis of Crohn's disease - Your disease is currently in remission (low disease activity scores and inflammation markers) - You have had 2 or more relapses in recent years - You have never tried acupuncture before - You are on minimal or no medications (or specific low-dose medications only) **You may NOT be eligible if...** - You are pregnant, recently pregnant, or breastfeeding - You have a serious organ disease, psychotic illness, or complex intestinal complications (such as fistulas, abscesses, or bowel obstruction) - Your skin in the acupuncture areas is damaged or diseased Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHER"Harmonizing Shaoyang, nourishing spleen and kidney with warmth" Acupuncture Group

Patients receiving acupuncture and mild moxibustion, whom were treated 2 times per week for 12 weeks and followed up for 40 weeks. The first group of acupoints is that CV4 and Bilateral ST37, SP6, SP4, KI3, LI11, SJ4 and GB26 were selected for acupuncture and CV12 and bilateral ST36 and GB41 were selected for moxibustion. The second group of acupoints is that CV12 and Bilateral ST36, GB41, SP4, KI3, LI11, SJ4 and GB26 were selected for acupuncture and CV4 and bilateral SP6 and GB34 were selected for moxibustion. These two groups are alternate. After deqi sensation was even reinforcing and reducing. The surface temperature of acupoints was maintained at 43℃± 1℃ for moxibustion. During each treatment, acupuncture and mild moxibustion are performed simultaneously, both lasting for 30 minutes.

OTHER"Nourishing spleen and kidney with warmth" Acupuncture Group

Patients receiving acupuncture and mild moxibustion, whom were treated 2 times per week for 12 weeks and followed up for 40 weeks. The first group of acupoints is that CV4 and Bilateral ST37, SP6, SP4, KI3 and LI11 were selected for acupuncture and CV12 and bilateral ST36 were selected for moxibustion. The second group of acupoints is that CV12 and Bilateral ST36, SP4, KI3 and LI11 were selected for acupuncture and CV4 and bilateral SP6 were selected for moxibustion. These two groups are alternate. After deqi sensation was even reinforcing and reducing. The surface temperature of acupoints was maintained at 43℃± 1℃ for moxibustion. During each treatment, acupuncture and mild moxibustion are performed simultaneously, both lasting for 30 minutes.