RecruitingNCT06554197

Evaluation of CMV/EBV-CMI in Haploid HSCT

Evaluation of Cytomegalovirus and Epstein-Barr Virus Specific Immune Reformulation in Prophylaxis for Cytomegalovirus in Haploid Hematopoietic Stem Cell Transplantation


Sponsor

The First Affiliated Hospital of Soochow University

Enrollment

60 participants

Start Date

Aug 13, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this prospective, open-label, Single Arm, single-center study is to evaluate the cytomegalovirus and Epstein-Barr virus specific immune reestablishment for patients with hemopathy undergoingin prophylaxis for cytomegalovirus in haploid hematopoietic stem cell transplantation(haplo-HSCT) .


Eligibility

Min Age: 16 YearsMax Age: 60 Years

Inclusion Criteria3

  • All patients were diagnosed with hemopathy.
  • All patients should have the indication of Haploidentical hematopoietic stem cell transplant and receive the prophylaxis for cytomegalovirus.
  • All patients should sign an informed consent document indicating that they understand the purpose of and procedures required for the study and be willing to participate in the study.

Exclusion Criteria1

  • Patients with any conditions not suitable for the trial (investigators' decision).

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Interventions

DIAGNOSTIC_TESTCMV/EBV-CMI

The CMV/EBV-CMI is tested before conditioning regimen and 30 days, 45 days, 60 days, 90 days, 120 days, 180 days after transplantation.


Locations(1)

First Affiliated Hospital of Soochow University

Suzhou, Jiangsu, China

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NCT06554197


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