Effect of Renal Denervation on Bood Pressure in Patients on Hemodialysis

This study is testing whether a procedure called renal denervation — where nerve signals to the kidneys are interrupted using a thin tube (catheter) — can help lower blood pressure in patients whose high blood pressure is extremely hard to control, even while on dialysis for kidney failure. **You may be eligible if...** - You are 18 or older with end-stage kidney disease on regular dialysis - You have uncontrolled high blood pressure despite taking at least 3 different blood pressure medications - Your dialysis routine has been stable for at least 3 months **You may NOT be eligible if...** - You have had a prior renal denervation procedure - You have had a heart attack, stroke, or unstable chest pain in the past 3 months - You have significant narrowing or structural problems in your kidney arteries - You have only one functioning kidney or a transplanted kidney - You have high blood pressure caused by a hormonal condition other than sleep apnea Talk to your doctor to see if this trial is right for you.