RecruitingNot ApplicableNCT06560385

Alleviation of Alopecia in Breast Cancer Patient Using Synbiotics Formula

A Pilot, Double-blind, Randomised, Placebo-controlled Trial on the Efficacy of a Synbiotic Formula (BLHK03) in Alleviating Chemotherapy-induced Alopecia (CIA) in Breast Cancer Patients


Sponsor

GenieBiome Limited

Enrollment

40 participants

Start Date

Sep 11, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to explore the efficacy and safety of a synbiotic formula (BLHK03) in alleviating chemotherapy-induced alopecia (CIA) in breast cancer patients and the compositional and functional changes in the gut microbiome of breast cancer patients undergoing chemotherapy and treatment with BLHK03.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether a synbiotic supplement (a combination of probiotics and prebiotics) can reduce or prevent chemotherapy-related hair loss in breast cancer patients by supporting the gut microbiome during treatment. **You may be eligible if...** - You are a woman aged 18–60 with newly diagnosed stage I, II, or III breast cancer - Your planned chemotherapy includes an anthracycline or taxane drug - You have not yet started chemotherapy **You may NOT be eligible if...** - You already have significant hair thinning or are using scalp cooling - You are pregnant or breastfeeding - You have a serious heart, liver, kidney, or lung condition - You have used antibiotics, probiotics, or prebiotics in the past month - You have a history of allergy to probiotics or lactose Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTBLHK03

BLHK03 consists of a blend of probiotics (20 billion CFU in 1 sachet) and prebiotic compounds

DIETARY_SUPPLEMENTActive placebo

Active placebo contains 5mcg of Vitamin B7


Locations(2)

GenieBiome Limited

Hong Kong, Hong Kong

Heal Medical

Hong Kong, Hong Kong

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NCT06560385


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