RecruitingNot ApplicableNCT06563544

FCV Vs VCV in Obstructive and Asthmatic Patients

Flow Versus Volume-Controlled Ventilation in Intubated Obstructive and Asthmatic Patients


Sponsor

Erasmus Medical Center

Enrollment

10 participants

Start Date

Oct 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this physiological pilot study with a randomized crossover design is to study the effect of Flow-controlled ventilation (FCV) on the minute volume compared to Volume-controlled ventilation (VCV) in intubated patients with an exacerbation of their asthma or COPD. Our hypothesis is that FCV will results in a lower minute volume compared to VCV in this patient category. Patients will be randomized between two ventilation sequences, namely 90 minutes of FCV followed by 90 minutes of VCV or vice versa.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two modes of mechanical ventilation — flow-controlled ventilation (FCV) versus volume-controlled ventilation (VCV) — in patients who are on a breathing machine due to a severe asthma or COPD flare-up, to determine which method ventilates the lungs more evenly and causes less strain. **You may be eligible if...** - You are 18 or older - You are on a mechanical ventilator through a breathing tube (intubated) - You were intubated because of a severe flare-up of asthma or COPD - You have been intubated for 72 hours or less **You may NOT be eligible if...** - You have severe mucus buildup requiring suctioning more than 5 times per nursing shift - You have an untreated collapsed lung (pneumothorax without drainage) - You have dangerously low blood pressure not responding to fluids or medications - You have high pressure in your brain or skull - Your breathing tube has a very small inner diameter (6mm or less) - Withdrawal of life support or palliative care is being planned - You have a pacemaker (ICD) or recent lung surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEFCV

90 minutes of FCV


Locations(2)

Erasmus Medical Center

Rotterdam, South Holland, Netherlands

Maasstad Hospital

Rotterdam, South Holland, Netherlands

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NCT06563544


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