Non-invasive Phrenic Nerve Stimulation in ARDS Patient
Non-invasive Phrenic Nerve Stimulation in ARDS Patients - a Feasibility Study
Southeast University, China
10 participants
Aug 1, 2024
INTERVENTIONAL
Conditions
Summary
Reduced diaphragmatic activity during mechanical ventilation can lead to diaphragmatic disuse atrophy, atelectasis, increased lung stress and strain, and hemodynamic impairment. This, in turn, may prolong the duration of mechanical ventilation, make weaning more difficult, and even increase mortality. Synchronizing phrenic nerve stimulation to promote diaphragmatic activity may prevent ventilator-induced lung injury and ventilator-induced diaphragm dysfunction, thereby improving patient outcomes. Surgically implanted phrenic nerve stimulation has been used in certain neurological disorders, but the effects of percutaneous non-invasive synchronized phrenic nerve stimulation in patients with ARDS undergoing mechanical ventilation remain unclear and require further investigation.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
non-invasive phrenic nerve stimulation
Locations(1)
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NCT06572280