RecruitingNot ApplicableNCT06573658

Neurophysiological Changes After Perturbation-based Training in Older Adults

Short-term Neurophysiological Changes After a Perturbation-based Training in Community-dwelling Older Adults: A Pilot Study


Sponsor

The Hong Kong Polytechnic University

Enrollment

88 participants

Start Date

Apr 18, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is an assessor-blinded neurophysiological study. Participants will be randomly assigned to a perturbation-based training (PBT) or a walking (control) group. Changes in postural stability and neurophysiology in the brain following PBT compared to walking exercise without perturbation will be investigated.


Eligibility

Min Age: 60 Years

Inclusion Criteria6

  • Aged ≥ 60 years old
  • Community-dwelling
  • Right-handed
  • Able to communicate effectively in Cantonese or Mandarin
  • Able to walk independently on level ground for ≥ 30 minutes
  • Abbreviated Mental Test (Hong Kong version) score ≥ 6

Exclusion Criteria5

  • Metal implants (e.g. pacemaker, artificial cochlea)
  • Uncorrected vision or hearing impairment
  • Osteoporosis
  • Hip or knee replacement within the last year
  • Musculoskeletal, cardiovascular, mental, or neurological disorders (such as Parkinson's disease) which can affect MRI examination, balance control, or exercise participation.

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Interventions

BEHAVIORALPerturbation-based balance training (PBT)

It will be a two-session training with each session lasting for approximately an hour. Perturbations will be induced during treadmill walking. Participants will be instructed to recover their balance and continue walking after the perturbations.

BEHAVIORALWalking exercise (control)

It will be a two-session training with each session lasting for approximately an hour. The same training duration and format will be used as the PBT group, except that no perturbations will be induced during the treadmill walking.


Locations(1)

The Hong Kong Polytechnic University

Hong Kong, Hong Kong

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NCT06573658


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