RecruitingPhase 3NCT06575192

Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

A Prospective, Multicenter, Open-Label, Non-Randomized, Controlled Pivotal Study to Evaluate the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix in Implant-Based Two Stage Prepectoral Breast Reconstruction Post-Mastectomy


Sponsor

AbbVie

Enrollment

783 participants

Start Date

Nov 5, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evaluate the safety and effectiveness of ARTIA in adult participants undergoing immediate, two-stage, implant-based breast reconstruction post-mastectomy.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria2

  • Participants who will undergo unilateral or bilateral mastectomy upon enrollment.
  • Participants who are willing and able to undergo immediate pre-pectoral two-stage breast reconstruction with ARTIA or without ADM.

Exclusion Criteria2

  • Has an existing carcinoma of the breast without planned mastectomy or residual gross local tumor of the breast after mastectomy.
  • Has any disease which is clinically known to impact wound healing ability, such as uncontrolled diabetes or history of compromised wound healing.

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Interventions

DEVICEARTIA Reconstructive Tissue Matrix

Surgical Implant

OTHERNo Intervention

No ADM


Locations(21)

Cedars-Sinai Medical Center /ID# 268326

Los Angeles, California, United States

UC Irvine Medical Center /ID# 267428

Orange, California, United States

Stanford University Medical Center CTRU - 800 Welch Road /ID# 264196

Palo Alto, California, United States

South Bay Plastic Surgeons /ID# 264192

Torrance, California, United States

University Of Colorado - Anschutz Medical Campus /ID# 268627

Aurora, Colorado, United States

University of Florida College of Medicine /ID# 267485

Gainesville, Florida, United States

Rush University Medical Center /ID# 275935

Chicago, Illinois, United States

Endeavor Health /ID# 266302

Northbrook, Illinois, United States

Johns Hopkins Hospital /ID# 265917

Baltimore, Maryland, United States

Washington University School of Medicine - St. Louis /ID# 264029

St Louis, Missouri, United States

University of Nevada - Main Campus /ID# 264017

Las Vegas, Nevada, United States

Rutgers New Jersey Medical School - Newark /ID# 264187

Newark, New Jersey, United States

Northwell Health Clinical Trials Office /ID# 268076

Lake Success, New York, United States

NYU Langone Medical Center /ID# 265621

New York, New York, United States

Atrium Health Wake Forest Baptist Medical Center /ID# 264382

Winston-Salem, North Carolina, United States

Ohio State University Comprehensive Cancer Center /ID# 266253

Columbus, Ohio, United States

Erlanger Health System /ID# 266608

Chattanooga, Tennessee, United States

East Tennessee State University /ID# 264321

Johnson City, Tennessee, United States

The University of Texas MD Anderson Cancer Center /ID# 264020

Houston, Texas, United States

University of Virginia /ID# 265098

Charlottesville, Virginia, United States

AG Aesthetic Center /ID# 264233

Vancouver, Washington, United States

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NCT06575192


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