RecruitingNot ApplicableNCT07209436

Impact of Pectoral Versus Paravertebral Blocks on Pain and Physical Well-Being in Implant-Based Breast Reconstruction


Sponsor

Amy Colwell

Enrollment

212 participants

Start Date

Nov 19, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The broad aim of this study is to compare the effectiveness of paravertebral and pectoral blocks on pain and physical well-being of patients undergoing immediate implant-based breast reconstruction.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study compares two types of nerve block (local anesthetic injections near the chest) used during implant-based breast reconstruction surgery — a pectoral (chest muscle) block versus a paravertebral (spine-level) block — to see which better controls post-surgery pain. **You may be eligible if...** - You are 18 or older - You are scheduled for immediate breast reconstruction using an implant (one or both sides) - Your reconstruction is planned for therapeutic (cancer removal) or prophylactic (preventive) reasons - You can understand the study and provide informed consent **You may NOT be eligible if...** - You are having delayed reconstruction - You have an allergy or contraindication to local anesthetics - You have a history of radiation therapy to the chest area - You are severely obese (BMI over 40) - You have kidney problems, chronic pain conditions (like fibromyalgia), or pre-existing nerve damage Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREParavertebral block (single injection)

Paravertebral block at preop

PROCEDUREPectoral block

Pectoral block at preop


Locations(1)

Massachusetts General Hospital

Boston, Massachusetts, United States

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NCT07209436


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