RecruitingPhase 1NCT06575738

Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents

Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide - in Adolescents (the PRESSURE Trial)


Sponsor

University of Colorado, Denver

Enrollment

40 participants

Start Date

Oct 11, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The study plans to learn more about what happens to the body after bariatric surgery in people 12 to 24 years old. The study aims to understand why people respond differently to bariatric surgery and how to define success beyond weight loss alone. The study also plans to learn more about whether a medication (semaglutide) can help people 12 to 24 years old who, between 1 and 2 years after bariatric surgery, have not lost as much weight as expected.


Eligibility

Min Age: 12 YearsMax Age: 24 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Injectable semaglutide and a behavioral approach called Standard postoperative care for people with adolescent obesity, anti-obesity agents, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 12 Years to 24 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGInjectable semaglutide

Subcutaneous weekly injectable semaglutide

BEHAVIORALStandard postoperative care

Standard postoperative care consists of behaviorally-focused interventions delivered by the interdisciplinary Bariatric Surgery Center team targeting nutrition, physical activity, sleep, and mental health at standard postoperative intervals.


Locations(1)

Childrens Hospital Colorado

Aurora, Colorado, United States

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NCT06575738


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